Hands-On Test Predicts Worsening Knee OA

Physical exam findings of patellofemoral grind may help predict which patients with knee osteoarthritis (OA) are likely to experience significant worsening of their disease, analysis of data from the Osteoarthritis Initiative showed.

Individuals with persistent patellofemoral grind had a greater annual loss of cartilage volume compared with those without this clinical finding (1.30% vs 0.90%, P<0.001), according to Yuanyuan Wang, MD, PhD, of Monash University in Melbourne, Australia, and colleagues.

They also had twice the risk of having a total knee replacement by 6 years (OR 2.10, 95% CI 1.30-3.38, P=0.002), the researchers reported online in Arthritis Care & Research.

The natural history of knee OA can vary notably among patients, and because of the increasing numbers of affected patients worldwide it has become critical to identify those who are most likely to progress, so as to better target healthcare resources.

Full story at MedPage Today