Scientists Find a Clue to Age-Related Memory Loss

Age-related memory loss is a distinct condition from pre-Alzheimer’s, new research shows, offering a hint that what we now consider the normal forgetfulness of old age might eventually be treatable. They discovered that a certain gene in a specific part of the hippocampus, the brain’s memory center, quits working properly in older people.

Scientists Find Clue to Age Related Memory LossScientists have found a compelling clue in the quest to learn what causes age-related memory problems and to one day be able to tell if those misplaced car keys are just a "senior moment" or an early warning of something worse.

[The recent] report offers evidence that age-related memory loss really is a distinct condition from pre-Alzheimer’s — and offers a hint that what we now consider the normal forgetfulness of old age might eventually be treatable.

Researchers at Columbia University Medical Center examined brains, young and old, donated from people who died without signs of neurologic disease. They discovered that a certain gene in a specific part of the hippocampus, the brain’s memory center, quits working properly in older people. It produces less of a key protein.

That section of the brain, called the dentate gyrus, has long been suspected of being especially vulnerable to aging. Importantly, it’s a different neural neighborhood than where Alzheimer’s begins to form.

Full story of age related memory loss at Sci-Tech Today

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