Study Will Test Transplantation Of Gene-Modified Cells To Explore A Potential Cure For HIV Infection

Study Will Test Transplantation Of Gene-Modified Cells To Explore A Potential Cure For HIV Infection

By Medical News Today


Whether a stem cell transplant using an HIV-infected person’s own genetically modified immune cells can become a cure for the disease is the focus of a new $20 million, five-year research grant award announced today by the National Institutes of Health to Fred Hutchinson Cancer Research Center.

Hutchinson Center researchers will use the grant to lead a multifaceted team of scientists and institutions to study whether a person’s own stem cells can be engineered to deny HIV entry into the body’s blood cells. The researchers also will work to develop tools to eradicate existing reservoirs of infection in the body.

"Funding for research to find a cure for HIV-infected persons represents a paradigm shift," said Keith Jerome, M.D., Ph.D., an expert in viral infections and co-principal investigator of the grant. "HIV has been an incurable, lifelong infection that at best sentences people to a lifetime of complex drug therapies. Now the research field is shifting to address the possibility of a cure. No one would have talked about this approach five years ago."

Full story at Medical News Today