Stem Cell Model Aids Neuron Resilience In ALS

Researchers at Karolinska Institutet in Sweden have developed a stem cell based model in order to study the resilience and vulnerability of neurons in the neurodegenerative disease ALS.

The results, published in the journal Stem Cell Reports, may help aid in the identification of new genetic targets for treatments protecting sensitive neurons, they suggest, in a media release from Karolinska Institutet.

“This cell culture system can help identify new genes contributing to the resilience in oculomotor neurons that could be used in gene therapy to strengthen sensitive motor neurons,” explains Eva Hedlund, docent at the Department of Neuroscience at Karolinska Institutet, who led the study.

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