Authors of a new study say they’ve found a set of predictors that could help providers identify which cardiac rehabilitation (CR) patients are at risk of making lower gains in exercise capacity (EC) from the intervention.
Researchers analyzed before-and-after results from the 6-minute walk test (6MWT) among 541 patients enrolled in the Mayo Clinic Florida’s CR program, tracking distance as well as heart rate and blood pressure before and after each test. Next they compared post-CR 6MWT results with a range of health and demographic data including type of initial cardiac procedure, age, sex, body mass index (BMI), total cholesterol, low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (LDL), triglycerides, and use of lipid-lowering drugs (LLD) at baseline. Results were published in the American Journal of Cardiology.
When they looked at who didn’t achieve optimal EC after CR, researchers found a constellation of factors that they believe may be predictive of an individual’s likelihood of making substandard gains. In all, 9 major predictors were identified (listed here in descending order of effect): baseline distance on 6MWT, age, percutaneous coronary intervention (or PCI, as opposed to coronary artery bypass graft, or CABG), LDL-C level, gender, the interaction of LDL-C while on LLDs, systolic BP at rest, BMI, and triglyceride levels.