A study conducted by Evidation Health on behalf of Eli Lilly and Apple suggests that data collected from smart devices and digital apps might help speed up the diagnosis of early stages of Alzheimer’s disease.
The study, “Developing Measures of Cognitive Impairment in the Real World from Consumer-Grade Multimodal Sensor Streams,” was performed in order to assess the feasibility of using smart devices to differentiate individuals with mild cognitive impairment (MCI) and early Alzheimer’s disease (AD) dementia from healthy controls.
MCI is the clinically symptomatic, pre-dementia stage of AD; cognitive deficits do not yet impair the ability to function at work or in daily activities.
Exercise training alters brain blood flow and improves cognitive performance in older adults, though not in the way you might think. A new study published by University of Maryland School of Public Health researchers in the Journal of Alzheimer’s Disease showed that exercise was associated with improved brain function in a group of adults diagnosed with mild cognitive impairment (MCI) and a decrease in the blood flow in key brain regions.
“A reduction in blood flow may seem a little contrary to what you would assume happens after going on an exercise program,” explained Dr. J. Carson Smith, associate professor in the Department of Kinesiology. “But after 12-weeks of exercise, adults with MCI experienced decreases in cerebral blood flow. They simultaneously improved significantly in their scores on cognitive tests.”
Dr. Smith explains that for those beginning to experience subtle memory loss, the brain is in “crisis mode” and may try to compensate for the inability to function optimally by increasing cerebral blood flow. While elevated cerebral blood flow is usually considered beneficial to brain function, there is evidence to suggest it may actually be a harbinger of further memory loss in those diagnosed with MCI. The results of the study by Dr. Smith and his team suggest exercise may have the potential to reduce this compensatory blood flow and improve cognitive efficiency in those in the very early stages of Alzheimer’s Disease.
Further evidence that doing aerobic exercise can preserve brain health and function — and thereby reduce the risk of dementia — is revealed in a study of older individuals with slight but noticeable declines in memory and thinking.
The researchers — from the University of Texas Southwestern Medical Center in Dallas — think that their study is the first to use an objective measure of aerobic capacity to assess the relationship between white matter integrity, cognitive performance, and cardiorespiratory fitness in older individuals with mild cognitive impairment (MCI).
“This research,” explains first study author Kan Ding, an assistant professor of neurology and neurotherapeutics, “supports the hypothesis that improving people’s fitness may improve their brain health and slow down the aging process.”